Chair of Research: 2009

Eric C. Holland, MD, PhD
Memorial Sloan-Kettering Cancer Center, New York, New York
Investigating the role of DNA damage response in gliomagenesis and “cancerstem cell” resistance to irradiation

This is a gene study of chk2’s role as a tumor suppressor. Chk2 is a protein that inhibits cell division and growth. The study plans to identify novel characteristics of a protein involved in the repair of DNA damage, the control of tumor growth, and response of tumors to radiation therapy.

Tumor: High grade gliomas, Medulloblastoma