2010 Grant

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<IMG SRC="590806e0.jpg" border=0 width="128" height="110" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div>  <IMG SRC="590806e0.jpg" border=0 width="128" height="110" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div>  <IMG SRC="590806e0.jpg" border=0 width="128" height="110" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div>  </div> </NOBR></tD> <tD VALIGN=TOP WIDTH="615"><div> <FONT SIZE="5" COLOR="#000066" FACE="Arial" ><B>Billy Grey</B> </FONT><A HREF="2011grant.htm" TARGET="_top" TITLE="2011 Grant "><U><2011</U></A><A HREF="2011grant.htm" TARGET="_top" TITLE="2011 Grant "><U><B> </B></U></A><B><2010</B> <<A HREF="2009grant.htm" TARGET="_top" TITLE="2009 Grant "><U>2009</U></A> <<A HREF="id43.htm" TARGET="_top" TITLE="2008 Grant "><U>2008</U></A> < <A HREF="id39.htm" TARGET="_top" TITLE="2007 Grant "><U>2007</U></A> < <A HREF="id36.htm" TARGET="_top" TITLE="20052006 Grant "><U>2005-2006</U></A> < <A HREF="id32.htm" TARGET="_top" TITLE="2004 Grant "><U>2003-2004</U></A> < <A HREF="id30.htm" TARGET="_top" TITLE="2002 Grant"><U>2002</U></A></div> <bR> <div> <B>Chair of Research: 2010</B></div> <div> <B>(retrieved from </B><A HREF="http://www.braintumor.org/research/research-dollars-spent/current-research/" TARGET="_top" TITLE="http://www.braintumor.org/research/resea"><U><B>http://www.braintumor.org/research/research-dollars-spent/current-research/</B></U></A></div> <bR> <div> Mark W. Kieran, MD, PhD</div> <div> <B>Dana Farber Cancer Institute, Boston, Massachusetts</B></div> <div> <I>Paraffin-based sequencing of the human kinome in pediatric ATRT</I></div> <bR> <div> This project will study the molecular pathways that drive AT/RT (atypical teratoid rhabdoid tumor) formation and growth. Gene expression array analysis will be performed on a large series (up to 200 samples) of AT/ RT and compared using a number of exploratory analyses. Whole genome mutational analysis in AT/RT has not been previously studied and identification of specific mutations will provide important information on focusing further efforts on specific pathways.</div> <div> <I>Matched to </I><I>Billy Grey Chair of Research</I></div> <div> Tumor: ATRT</div> <bR> </tD> </tR> </TABLE></B></div> <bR> <bR> <bR> <bR> </td> </tr></table></body>