2002 Grant

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TARGET="_top" TITLE="2004 Grant "><U>2003-2004</U></A><B> < </B><A HREF="id30.htm" TARGET="_top" TITLE="2002 Grant"><U><B>2002</B></U></A></div> <bR> <div> <B>Chair of Research: 2002</B></div> <div> His determination and love continues to live within all of us and was exemplified at the awarding of the first $50,000 grant under The Billy Grey Research Chair at the annual Brain Tumor Society's Symposium on September 21, 2002.</div> <div> <B>Evan M. Hersh, MD.</B></div> <div> University of Arizona, Tucson, AZ</div> <div> <B>Dendritic Cell And Dexosome Interaction With Glioblastoma Multiforme</B></div> <div> <TABLE BORDER="2" CELLPADDING="2" CELLSPACING="1" WIDTH="128" BORDERCOLORLIGHT="#000033" BORDERCOLORDARK="#000099" FRAME="BOX" RULES="ALL" ALIGN="LEFT" HSPACE="0" VSPACE="0" BGCOLOR=#000066 > <tR> <tD VALIGN=TOP HEIGHT= 156 WIDTH="116"><div>  <IMG SRC="06e73850.png" border=0 width="115" height="133" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> </tD> </tR> </TABLE></div> <bR> <div> This project will study how brain tumor cells and substances extracted from them can stimulate the immune system. Research has shown that the immune system can be stimulated to kill cancer cells. Immunotherapy, such as cancer vaccines, is showing tremendous promise in brain tumors.</div> <bR> <div> This study will investigate two new approaches to stimulate anti-brain tumor immunity with: (1) dendritic cells, special white blood cells, that can strongly stimulate the development of killer white blood cells, and (2) dexosomes, microscopic particles derived from dendritic cells and even more powerful in stimulating the immune system. Human brain tumor cells or extracts of tumor cells will be added to dendritic cells and dexosomes and used to stimulate lymphocytes ( the body's immune cells). These laboratory experiments will show how the anti-brain tumor response works and the optimal techniques and conditions to stimulate effective brain tumor immunotherapy.</div> <bR> <div> <I>September 21,2002 </I></div> <div> <I>The Brain Tumor Society </I></div> <div> <I>Research Society Research Grant Awards and Annual Meeting </I></div> <div> <I>Boston Marriott  ~ Quincy, Massachusetts</I></div> </tD> </tR> </TABLE></div> <bR> <bR> <bR> <div> <I><B> </B></I><FONT SIZE="5" COLOR="#000066" FACE="Arial" ><I><B> </B></I></FONT></div> <div> <I><B> <TABLE BORDER="0" CELLPADDING="2" CELLSPACING="1" WIDTH="909" BORDERCOLORLIGHT="#C0C0C0" BORDERCOLORDARK="#808080" FRAME="BOX" RULES="ALL" HSPACE="0" VSPACE="0" > <tR> <tD VALIGN=TOP HEIGHT= 58 WIDTH="903"><bR> <bR> </tD> </tR> </TABLE></B></I></div> <bR> </td> </tr></table></body>